| Date | Year | Opponent | Stadium | Location |
|---|---|---|---|---|
| September 3 | 2011 | Northwestern Wildcats | Alumni Stadium | Chestnut Hill, MA |
| September 10 | 2011 | Central Florida Knights | Bright House Networks Stadium | Orlando, FL |
| September 17 | 2011 | Duke Blue Devils* | Alumni Stadium | Chestnut Hill, MA |
| September 24 | 2011 | Massachusetts Minutemen | Alumni Stadium | Chestnut Hill, MA |
| October 1 | 2011 | Wake Forest Demon Deacons* | Alumni Stadium | Chestnut Hill, MA |
| October 8 | 2011 | Clemson Tigers* | Memorial Stadium | Clemson, SC |
| October 15 | 2011 | OPEN DATE | ||
| October 22 | 2011 | Virginia Tech Hokies* | Lane Stadium | Blacksburg, VA |
| October 29 | 2011 | Maryland Terrapins* | Byrd Stadium | College Park, MD |
| November 3 | 2011 | Florida St. Seminoles* | Alumni Stadium | Chestnut Hill, MA |
| November 12 | 2011 | N.C. State Wolfpack* | Alumni Stadium | Chestnut Hill, MA |
| November 19 | 2011 | Notre Dame Fighting Irish | Notre Dame Stadium | South Bend, IN |
| November 26 | 2011 | Miami Hurricanes* | Sun Life Stadium | Coral Gables, FL |
* Denotes ACC game