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Boston College took a step forward, then two steps back in the second quarter, as a late interception return gave Wake Forest a 14-point lead at intermission.
After a lengthy BC drive ended with a Brown touchdown pass to Jon Hilliman, the Eagles forced a punt and looked to tie the game.
Unfortunately for the Eagles, Brown's next pass bounces off the hands of receiver Kobay White, and was returned 30 yards by Wake's Essang Bassey for a touchdown.
BC will start the second half on defense, and will have its work cut out for it.